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生物来源
mouse
质量水平
抗体形式
purified antibody
克隆
RT97, monoclonal
种属反应性
rat, human, pig, avian, chicken, reptile
种属反应性（根据同源性预测）
mammals
制造商/商品名称
Chemicon®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
特异性
The clone RT97 recognizes the 200 kDa neurofilament polypeptide in a number of mammalian and avian species. Tumours specifically recognized include phaeochromocytoma, paraganglioma, ganglioneuroblastoma and other tumours of neuronal origin.
KNOWN SPECIES CROSS REACTIVITY: Recognizes rat, chicken, pig and reptile
KNOWN SPECIES CROSS REACTIVITY: Recognizes rat, chicken, pig and reptile
应用
Anti-Neurofilament 200 kDa Antibody, clone RT97 detects level of Neurofilament 200 kDa & has been published & validated for use in IH, IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Staining of both frozen and paraffin wax embedded tissue sections
Strong staining of neuronal processes in a variety of tissues
Optimal working dilutions must be determined by the end user.
Strong staining of neuronal processes in a variety of tissues
Optimal working dilutions must be determined by the end user.
外形
Format: Purified
The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Oxaliplatin and related chemotherapeutic drugs cause painful chronic peripheral neuropathies in cancer patients. We investigated changes in neuronal size profiles and neurofilament immunoreactivity in L5 dorsal root ganglion (DRG) tissue of adult female Wistar rats after multiple-dose treatment with oxaliplatin
2-(Cyclohexylamino)-1-(4-cyclopentylpiperazin-1-yl)-2-methylpropan-1-one, a novel compound with neuroprotective and neurotrophic effects in vitro.
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Pain is normally mediated by nociceptive Aδ and C fibers, while Aβ fibers signal touch. However, after nerve injury, Aβ fibers may signal pain. Using a genetic model, we tested the hypothesis that phenotypic switching in neurotransmitters expressed by Aβ
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