推荐产品
生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse, rat, human
製造商／商標名
Chemicon®
技術
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... QKI(9444)
一般說明
QKI 是一种RNA结合蛋白，在髓鞘形成中起主导作用。通过调节pre-mRNA剪接、mRNA输出、mRNA稳定性和蛋白质翻译起作用。它通过可变剪接调节。
特異性
QKI-7 （Quaking 蛋白）该抗体识别~42 kDa蛋白。
免疫原
来自小鼠QKI-7的合成肽。
應用
抗-QKI-7抗体是针对QKI-7的抗体，可用于IP & WB。
研究子类别
发育神经科学
RNA结合蛋白（RBP）
发育神经科学
RNA结合蛋白（RBP）
研究类别
神经科学
神经科学
外觀
液体。
血清
儲存和穩定性
自收到之日起，在 -20°:C 以未稀释的等分试样可保存 12 个月。应避免反复冻/融循环。
分析報告
对照
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Hiroaki Hojo et al.
The Journal of biological chemistry, 295(2), 390-402 (2019-12-04)
MicroRNA-122 (miR-122) is highly expressed in hepatocytes, where it plays an important role in regulating cholesterol and fatty acid metabolism, and it is also a host factor required for hepatitis C virus replication. miR-122 is selectively stabilized by 3' adenylation
Zhejia Zhang et al.
Oncology letters, 15(4), 5841-5848 (2018-03-21)
Thyroid cancer is the most frequently occurring type of endocrine tumor, with a rapidly increasing incidence rate. MicroRNA (miR)-574-5p is a candidate oncogene in various types of cancer. The present study identified that miR-574-5p affected the cell cycle distribution and
Kristina Sakers et al.
Nature communications, 12(1), 1537-1537 (2021-03-23)
Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demonstrated to have regulated
Ruben G de Bruin et al.
Epigenomes, 4(1) (2020-02-13)
In the pathophysiologic setting of acute and chronic kidney injury, the excessive activation and recruitment of blood-borne monocytes prompts their differentiation into inflammatory macrophages, a process that leads to progressive glomerulosclerosis and interstitial fibrosis. Importantly, this differentiation of monocytes into
Xinyun Chen et al.
Nature communications, 12(1), 89-89 (2021-01-06)
The RNA-binding protein QKI belongs to the hnRNP K-homology domain protein family, a well-known regulator of pre-mRNA alternative splicing and is associated with several neurodevelopmental disorders. Qki is found highly expressed in developing and adult hearts. By employing the human
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