8.18586

Isophorone diisocyanate

(mixture of cis- and trans-isomers) for synthesis

• 别名: Isophorone diisocyanate, 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcyclohexane, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
• 经验公式（希尔记法）: C₁₂H₁₈N₂O₂
• CAS号: 4098-71-9
• 分子量: 222.28
• MDL號碼: MFCD00064956
• 分類程式碼代碼: 12352118
• 酶委員會索引編號: 223-861-6
• NACRES: NA.22

属性

• 蒸汽壓力: 0.0004 hPa ( 20 °C)
• 品質等級: 200
• 化驗: ≥99.0% (GC)
• 形狀: liquid
• 自燃溫度: 430 °C
• 效力: 4825 mg/kg LD₅₀, oral (Rat); >7000 mg/kg LD₅₀, skin (Rat)
• expl. lim.: 0.7-4.5 % (v/v)
• bp: 158-159 °C/13 hPa
• mp: -60 °C
• 轉變溫度: flash point 155 °C
• 溶解度: 0.015 g/L (slow decomposition)
• 密度: 1.06 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C12H18N2O2/c1-11(2)4-10(14-9-16)5-12(3,6-11)7-13-8-15/h10H,4-7H2,1-3H3
• InChI 密鑰: NIMLQBUJDJZYEJ-UHFFFAOYSA-N

说明

應用

• Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.: This study explores the development of thermoresponsive random poly(ether urethanes) synthesized using Isophorone diisocyanate. These polymers exhibit adjustable lower critical solution temperatures (LCSTs), making them suitable for controlled anticancer drug delivery applications. The research highlights the potential of Isophorone diisocyanate in creating advanced materials for medical use, specifically in drug delivery systems (Sardon et al., 2015).

分析報告

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.060 - 1.062
Identity (IR): passes test

安全信息

• 象形圖: GHS06,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H315 - H317 - H319 - H330 - H334 - H335 - H411
• 防範說明: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 1 Inhalation - Aquatic Chronic 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 325.4 °F - closed cup
• 閃點（°C）: 163 °C - closed cup