524394

4α-Phorbol-12,13-didecanoate

>99% (HPLC), solid, PDD and PMA negative control, Calbiochem^®

• 别名: 4α-Phorbol-12,13-didecanoate, 4αPDD, PKC Activator I, Negative Control
• 经验公式（希尔记法）: C₄₀H₆₄O₈
• CAS号: 27536-56-7
• 分子量: 672.93
• MDL编号: MFCD00036737
• UNSPSC代码: 12352211
• NACRES: NA.77

属性

• 产品名称: 4α-Phorbol-12,13-didecanoate, Inactive on mouse skin as an inflammatory and tumor-promoting agent.
• 质量水平: 100
• 方案: >99% (HPLC)
• 表单: solid
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze
• 溶解性: DMSO: soluble; ethanol: soluble
• 运输: ambient
• 储存温度: −20°C
• SMILES字符串: O([C@]21[C@H]([C@H]3[C@@]([C@H]4[C@@](CC(=C3)CO)(C(=O)C(=C4)C)O)([C@@H]([C@H]2OC(=O)CCCCCCCCC)C)O)C1(C)C)C(=O)CCCCCCCCC
• InChI: 1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
• InChI key: DGOSGFYDFDYMCW-OEFRVDPMSA-N

说明

一般描述

Inactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).

Reported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).

生化/生理作用

Cell permeable: no

Primary Target
A negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Highly Toxic (H)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

其他说明

Akiguchi, I., et al. 1993. Endocrinology 138, 379.
Clarke, B.L., et al. 1993. Endocrinology132, 1168.
Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med.121, 337.
Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol.43, 223.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS06,GHS08,GHS05
• 警示用语：: Danger
• 危险声明: H300 + H310 + H330,H314,H317,H334,H351
• 预防措施声明: P201 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危险分类: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• 储存分类代码: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable