5.08161

SNC80

• 别名: SNC80, δ Opioid Receptor Agonist, SNC80
• 经验公式（希尔记法）: C₂₈H₃₉N₃O₂
• CAS号: 156727-74-1
• 分子量: 449.63
• MDL號碼: MFCD00672673
• 分類程式碼代碼: 51111800
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 品質等級: 100
• 形狀: solid
• 效力: 0.32 μM IC₅₀
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: cream
• 溶解度: 1 M HCl: 100 mM; DMSO: 20 mM
• 儲存溫度: −20°C
• InChI: 1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1
• InChI 密鑰: KQWVAUSXZDRQPZ-UMTXDNHDSA-N

说明

一般說明

A very potent and selective δ opioid receptor agonist (IC₅₀ = 0.32 µM). Shown to induce dose- and time-dependent antinociception after i.c.v., i.th. and i.p. administration in mice. Widely used in studies of depression and inflammatory injuries. It is also reported to be acted upon heteromeric u-d receptors.

生化／生理作用

Primary Target
Dela opioid receptor

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Pradhan, A., et al., 2013. Mol Pain.9, 8.
Saitoh, A., et al., 2012. Curr. Neuropharmacol.10, 231.
Metcalf. M. et al. 2012. ACS Chem. Neurosci.3, 505.
Bilsky, J., et al. 1995. J. Pharmacol. Exp. Ther.273, 359.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable