5.05016

CX546

• 别名: CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546
• 经验公式（希尔记法）: C₁₄H₁₇NO₃
• CAS号: 215923-54-9
• 分子量: 247.29
• MDL编号: MFCD01860868
• UNSPSC代码: 12352200
• NACRES: NA.77

属性

• 方案: ≥98% (TLC)
• 质量水平: 100
• 表单: solid
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze; protect from light
• 颜色: off-white
• 溶解性: DMSO: soluble
• 储存温度: 2-8°C
• SMILES字符串: N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2
• InChI: 1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
• InChI key: LJUNPHMOGNFFOS-UHFFFAOYSA-N

说明

一般描述

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

生化/生理作用

Primary Target
AMPA

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable