23-057-M

Smac/DIABLO

• 别名: Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase (Smac)
• UNSPSC代码: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

属性

• 生物来源: human
• 质量水平: 100
• 表单: liquid
• 制造商/商品名称: Upstate^®
• 技术: activity assay: suitable
• NCBI登记号: NM_019887

说明

一般描述

Smac/DIABLO is a mitochondrial protein that is proteolytically processed and released during apoptosis along with cytochrome c and other pro-apoptotic factors. Once in the cytosol, Smac/DIABLO binds to inhibitors of apoptosis (IAP) proteins and disrupts the ability of the IAPs to inhibit caspases 3, 7, and 9 thereby promoting apoptosis. Along with several other pro-apoptotic proteins, Smac/DIABLO has been shown to be a substrate for the ubiquitin ligase XIAP.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H317
• 预防措施声明: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危险分类: Skin Sens. 1
• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable