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化驗
≥95% (SDS-PAGE)
形狀
solid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
溶解度
water: 20 mg/mL
儲存溫度
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI 密鑰
QYSGYZVSCZSLHT-UHFFFAOYSA-N
一般說明
人血清白蛋白(HSA)是可溶性的非糖基化球状蛋白单体,是血浆中含量最为丰富的蛋白。由I、II和III三个同源结构域组成多个结构域的蛋白质。每个结构域包含子域A和B,具有相同的结构基元。HSA基因位于人类染色体4q13.3上。
生化/生理作用
人血清白蛋白(HSA)是脂肪酸、甲状腺激素和类固醇的主要载体蛋白。对细胞外液量的稳定起关键作用。HSA可用作疫苗和治疗性蛋白质药物的赋形剂。还可用作疫苗和药物生产中的细胞培养基补充剂。HSA用于治疗血液透析、急性肝功能衰竭、慢性肝病等。HSA适用于各种生物应用,包括配体捕获、纳米给药和融合蛋白等。
警告
毒性:标准处理(A)
重構
复溶后,等分并冷冻保存(-20°C)。储备溶液在-20°C下可稳定保存至多6个月。
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity
Frontiers in physiology, 5, 299-299 (2014-08-28)
Serum albumin is a multi-functional protein that is able to bind and transport numerous endogenous and exogenous compounds. The development of albumin drug carriers is gaining increasing importance in the targeted delivery of cancer therapy, particularly as a result of
Proceedings of the National Academy of Sciences of the United States of America, 108(47), 19078-19083 (2011-11-02)
Human serum albumin (HSA) is widely used in clinical and cell culture applications. Conventional production of HSA from human blood is limited by the availability of blood donation and the high risk of viral transmission from donors. Here, we report
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