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Merck
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文件

1.08218

Supelco

三氟乙酸 溶液

(25% solution in water) for protein sequenation

别名:

TFA

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About This Item

线性分子式:
CF3COOH
CAS号:
分子量:
114.02
Beilstein:
5446934
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NB.21

品質等級

形狀

liquid

成份

Water, 74.5-75.5% Karl Fischer

濃度

24.5-25.5% (trifluoroacetic acid)

密度

1.12 g/cm3 at 20 °C

儲存溫度

15-25°C

SMILES 字串

OC(=O)C(F)(F)F

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI 密鑰

DTQVDTLACAAQTR-UHFFFAOYSA-N

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應用

Trifluoroacetic acid (TFA) can be used as a solvent in a reverse-phase HPLC system to separate peptides because it enhances peak resolution. It also has low absorption detection wavelengths and is relatively volatile and easily removed. For the majority of peptide separations, TFA has been used at concentrations ranging from 0.05 to 0.1%(6.5-13 mM).

分析報告

Assay (alkalimetric): 24.5 - 25.5 %
Identity (IR-spectrum): passes test
Density (d 20 °C/ 4 °C): 1.129 - 1.131
Fluorescence (at 254 nm): ≤ 2 ppb
Fluorescence (at 365 nm): ≤ 2 ppb
Water (according to Karl Fischer): 74.5 - 75.5 %

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

儲存類別代碼

8B - Non-combustible, corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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其他客户在看

Y Chen et al.
Journal of chromatography. A, 1043(1), 9-18 (2004-08-20)
Trifluoroacetic acid (TFA) remains the dominant mobile phase additive for reversed-phase high-performance liquid chromatography (RP-HPLC) of peptides after more than two decades since its introduction to this field. Generally, TFA has been employed in a concentration range of 0.05-0.1% (6.5-13

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