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P-055

Supelco

普萘洛尔 盐酸盐 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C16H21NO2·HCl
CAS号:
318-98-9
分子量:
295.80
EC號碼:
200-659-6
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

300

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

濃度

1.0 mg/mL in methanol (as free base)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

形式

single component solution

儲存溫度

−20°C

SMILES 字串

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI 密鑰

ZMRUPTIKESYGQW-UHFFFAOYSA-N

基因資訊

human ... ADRB1(153) , ADRB2(154)

相关类别

一般說明

一种经认证的参比溶液，适用于临床和诊断测试、尿液药物测试、法医分析或临床毒理学的LC/MS或GC/MS测试方法的校准器和控制的起始材料。普萘洛尔是一种交感神经非选择性受体阻滞剂，用于治疗高血压、焦虑和恐慌等多种疾病。该药物以Inderal®、Avlocardyl、Deralin和Dociton等许多商品名出售。

應用

<ul>
<li><strong>用于婴儿血管瘤的盐酸普萘洛尔溶液：</strong>研究人员已经开发出用于治疗婴儿血管瘤的盐酸普萘洛尔脂质体制剂，研究为儿科皮肤病学领域提供了一种针对性的治疗方法（Nifli et al., 2024）。</li>
<li><strong>盐酸普萘洛尔：</strong>对于溶剂沉积（solvent-deposited）的盐酸普萘洛尔在不同皮肤层经皮吸收的研究提供了对其性质的见解，例如它可以用作剂量和电离状态的应变量，并可作为校准标准品 （Tonnis et al., 2024）。</li>
</ul>

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Inderal is a registered trademark of Cranford Pharmaceuticals, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

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What doesn't kill may not make you stronger. β-blockers for asthma.
Shamsah Kazani et al.
American journal of respiratory and critical care medicine, 187(12), 1281-1281 (2013-06-19)
[Propanolol effective treatment for laryngo-tracheal hemangioma].
Markus Granholm et al.
Lakartidningen, 110(19-20), 947-948 (2013-06-12)
Philip M Short et al.
American journal of respiratory and critical care medicine, 187(12), 1308-1314 (2013-04-19)
Unblinded studies have shown improvements in airway hyperresponsiveness with chronic nadolol in steroid-naive patients with asthma. To assess the effects of chronic nonselective β-blockade as add-on to inhaled corticosteroids (ICS) in patients with asthma. A double-blind randomized placebo-controlled crossover trial
Jun Zhang et al.
Rapid communications in mass spectrometry : RCM, 27(7), 731-737 (2013-03-16)
Multiplexed liquid chromatography (LC) coupled with multiple-injection-chromatogram acquisition has emerged as the method of choice for high-speed discovery bioanalysis, because it significantly reduces injection-to-injection cycle time while maintaining the chromatography quality. Historically, systems utilizing this approach had been custom built
Practice gaps. Propranolol to treat hemangiomas of infancy: safety and side effect recognition.
Jonathan A Dyer
JAMA dermatology, 149(4), 485-486 (2013-05-30)
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