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Merck

G4802

Sigma-Aldrich

DL-甘油醛二聚体

95%

别名:

3,6-二羟基-1,4-二噁烷-2,5-二甲醇

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About This Item

经验公式(希尔记法):
C6H12O6
CAS号:
分子量:
180.16
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

95%

mp

144-145 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

OC[C@H]1O[C@@H](O)[C@H](CO)O[C@@H]1O

InChI

1S/2C3H6O3/c2*4-1-3(6)2-5/h2*1,3,5-6H,2H2

InChI 密鑰

NGNVWCSFFIVLAR-UHFFFAOYSA-N

一般說明

DL-Glyceraldehyde , dimer, a dimeric form of DL-glyceraldehyde is an organic compound that possesses a symmetrical p-dioxan crystalline structure with equatorially bonded hydroxy and hydroxymethyl groups. It reacts with a primary alkyl amine to form a Schiff base, during the synthesis of DL-alanine derivatives.

應用

  • 醛还原酶活性:以DL-甘油醛二聚体为底物,研究冬青卫矛叶子产出醛还原酶的酶促特性,解析醛糖的还原过程,对于了解植物胁迫反应有重要意义(Negm, 1986)。
  • 还原酶功能:在人肝脏醛还原酶的纯化和鉴定中研究DL-甘油醛二聚体,着重它的代谢解毒作用,对于涉及药物代谢和毒性的应用有重要意义(Petrash and Srivastava, 1982)。
  • 原生动物代谢通路:以DL-甘油醛二聚体为底物,研究束状带短膜虫(Crithidia fasciculata)产出的醛还原酶的酶促特性,解析原虫的代谢通路,对于开发抗寄生虫感染疗法有重要意义(Kobayashi, 1982)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Non-enzymatic transformation of dl-glyceraldehyde, 1, 3-dihydroxyacetone, and pyruvaldehyde with primary amine to the same dl-alanine derivatives
Yande H, et al.
Tetrahedron Letters, 56, 4516-4519 (2015)
Experimental and Theoretical Study of the Products from the Spontaneous Dimerization of DL-and D-Glyceraldehyde
Federico G, et al.
Journal of the Brazilian Chemical Society, 16, 467-476 (2005)
Chan Mee Lee et al.
Archives of pharmacal research, 38(6), 1090-1098 (2014-10-16)
Aldose reductase (AR) is a key enzyme in the polyol pathway that is strongly implicated in the pathogenesis of diabetic complications. AR inhibitors have been proposed as therapeutic agents for diabetic complications through suppression of sorbitol formation and accumulation. In
Jae Sue Choi et al.
Archives of pharmacal research, 37(10), 1354-1363 (2014-07-06)
To investigate the effect of C-glycosylation at different positions of luteolin, the structure-activity relationships of luteolin and a pair of isomeric C-glycosylated derivatives orientin and isoorientin, were evaluated. We investigated the effects of C-glycosylation on the antioxidant, anti-Alzheimer's disease (AD)
Md Nurul Islam et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 55-62 (2014-04-10)
Vicenin 2, isolated from a traditionally used medicinal plant Artemisia capillaris, is a 6,8-di-C-glucoside of apigenin which has been previously reported to possess a wide variety of pharmacological activities including antioxidant, anti-inflammatory, anti-cancer, and hepatoprotective. However, there have not been

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