推荐产品
品質等級
化驗
≥95%
形狀
solid
反應適用性
reaction type: click chemistry
reagent type: cross-linking reagent
官能基
alkyne
carboxylic acid
儲存溫度
−20°C
SMILES 字串
O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2
InChI
1S/C17H12O4/c1-2-11-21-15-9-7-13(8-10-15)16(18)12-3-5-14(6-4-12)17(19)20/h1,3-10H,11H2,(H,19,20)
InChI 密鑰
URDMKFAPEKSQDV-UHFFFAOYSA-N
應用
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他說明
Technology Spotlight: Trifuctional Probe Building Blocks
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
相關產品
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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商品
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
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