720429

1H-Pyrazol-3-ylboronic acid hydrate

• 经验公式（希尔记法）: C₃H₅BN₂O₂ · xH₂O
• 分子量: 111.90 (anhydrous basis)
• MDL號碼: MFCD11044442
• 分類程式碼代碼: 12352103
• PubChem物質ID: 329763716
• NACRES: NA.22

属性

• 形狀: solid
• mp: 88-93 °C
• 儲存溫度: 2-8°C
• SMILES 字串: O.OB(O)c1cc[nH]n1
• InChI: 1S/C3H5BN2O2.H2O/c7-4(8)3-1-2-5-6-3;/h1-2,7-8H,(H,5,6);1H2
• InChI 密鑰: NXQCQMBEFQLICU-UHFFFAOYSA-N

说明

一般說明

1H-Pyrazol-3-ylboronic acid hydrate can be used as a reactant in the Suzuki-Miyaura coupling reaction to synthesize pyrazole derivatives by reacting with different aryl halides over the palladium catalyst.

應用

Reactant for:

• Preparation of receiver-amplifier, self-immolative dendrimers as potential platform for self-triggered multiple-release prodrugs
• Preparation of bifunctional water-soluble triazole-containing derivatives of ethyl(hydroxycamptothecin) via click chemistry and conjugation to monoclonal antibodies for anticancer therapy

• Intermediate for synthesis of oligo(ethylene glycol)-terminated alkanethiol amides useful for biosensors

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable