跳转至内容
Merck
所有图片(1)

文件

542709

Sigma-Aldrich

2,6-二氟苯磺酰胺

97%

登录查看公司和协议定价
所有图片(1)

About This Item

线性分子式:
F2C6H3SO2NH2
CAS号:
60230-37-7
分子量:
193.17
MDL號碼:
MFCD00729101
分類程式碼代碼:
12352100
PubChem物質ID:
24878626
NACRES:
NA.22

化驗

97%

mp

187-191 °C (lit.)

SMILES 字串

NS(=O)(=O)c1c(F)cccc1F

InChI

1S/C6H5F2NO2S/c7-4-2-1-3-5(8)6(4)12(9,10)11/h1-3H,(H2,9,10,11)

InChI 密鑰

RVVVGGCOFWWDEL-UHFFFAOYSA-N

一般說明

2,6-Difluorobenzenesulfonamide is a fluorinated benzenesulfonamide that can be prepared by reacting 2,6-difluorobenzenesulfonyl chloride with 29% ammonium hydroxide. It forms complexes with human carbonic anhydrase II (HCA). X-ray crystal structure of these complexes have been studied.

應用

2,6-Difluorobenzenesulfonamide can be prepared from N-(4-chlorophenyl)-N′-[(2,6-di fluorophenyl)-sulfonyl]urea.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Insect growth regulators. Analogs of TH-6038 and TH-6040.
Oliver JE, et al.
Journal of Agricultural and Food Chemistry, 24(5), 1065-1068 (1976)
Vijay M Krishnamurthy et al.
Chemistry, an Asian journal, 2(1), 94-105 (2007-04-19)
This paper describes a calorimetric study of the association of a series of seven fluorinated benzenesulfonamide ligands (C6H(n)F(5-n)SO2NH2) with bovine carbonic anhydrase II (BCA). Quantitative structure-activity relationships between the free energy, enthalpy, and entropy of binding and pKa and log
Shruthi Vaidhyanathan et al.
The Journal of pharmacology and experimental therapeutics, 356(2), 251-259 (2015-11-26)
Small molecule inhibitors targeting the mitogen-activated protein kinase pathway (Braf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase) have had success in extending survival for patients with metastatic melanoma. Unfortunately, resistance may occur via cross-activation of alternate signaling pathways. One approach to overcome
Shruthi Vaidhyanathan et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(8), 1292-1300 (2014-05-31)
Brain metastases are a major cause of mortality in patients with advanced melanoma. Adequate brain distribution of targeted agents for melanoma will be critical for treatment success. Recently, improvement in overall survival led to US Food and Drug Administration (FDA)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门