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Merck

328022

Sigma-Aldrich

4-甲基马尿酸

98%

别名:

N-(对甲苯甲酰)基甘氨酸, N-对甲苯酸甘氨酸

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About This Item

线性分子式:
CH3C6H4CONHCH2CO2H
CAS号:
分子量:
193.20
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

powder

mp

163-165 °C (lit.)

SMILES 字串

Cc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)

InChI 密鑰

NRSCPTLHWVWLLH-UHFFFAOYSA-N

一般說明

4-Methylhippuric acid is the major metabolite of xylene and has been determined in urine by gas chromatography.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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P T Mayer et al.
AAPS pharmSci, 2(2), E14-E14 (2001-12-14)
To explore the independence of functional group contributions to permeability of nonelectrolytes across egg lecithin bilayers, the transport rates were measured of a series of alpha-substituted p-methylhippuric acids (-H, -Cl, -OCH3, -CN, -OH, -COOH, and -CONH2) across egg lecithin lipid
Peter T Mayer et al.
Journal of pharmaceutical sciences, 91(3), 640-646 (2002-03-29)
The barrier domain solubility-diffusion theory of lipid bilayer permeability relates the permeability coefficient (P(m)) to the solute's partition coefficient (PC(barrier/w)) and diffusion coefficient (D(barrier)) in the ordered chain region of the bilayer that serves as the barrier region for polar
Measurement of exposure to xylenes by separate determination of m- and p-methylhippuric acids in urine.
M Morin et al.
Journal of chromatography, 210(2), 346-349 (1981-06-05)
G Bieniek et al.
British journal of industrial medicine, 38(3), 304-306 (1981-08-01)
The separation of hippuric and m-methylhippuric acid as toluene and m-xylene metabolites present in urine of people exposed simultaneously to toluene and xylene is described. Chloroform was used for hippuric and m-methylhippuric acid extraction. Satisfactory separation of these metabolites was
M Ogata et al.
International archives of occupational and environmental health, 58(2), 121-129 (1986-01-01)
A new method for the direct determination of hippuric acid (HA) and o-, m- and p-methylhippuric acids (MHAs) in the urine, metabolites of toluene and o-, m- and p-xylenes by high performance liquid chromatography (HPLC) is described. A stainless-steel column

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