287644

(1R,2R)-(-)-伪麻黄碱

98%

• 别名: α-(1-甲氨基乙基)苄醇, (-)-ψ-麻黄碱, (-)-伪麻黄碱, (1R,2R)-(-)-2-(甲氨基)-1-苯丙醇, l-伪麻黄碱
• 线性分子式: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS号: 321-97-1
• 分子量: 165.23
• Beilstein: 2803417
• EC號碼: 206-292-8
• MDL號碼: MFCD00002203
• 分類程式碼代碼: 12352116
• PubChem物質ID: 24857283
• NACRES: NA.22

属性

• 化驗: 98%
• 形狀: solid
• 光學活性: [α]20/D −51°, c = 0.6 in ethanol
• mp: 118-120 °C (lit.)
• SMILES 字串: CN[C@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m1/s1
• InChI 密鑰: KWGRBVOPPLSCSI-SCZZXKLOSA-N

说明

一般說明

(1R,2R)-(-)-Pseudoephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

應用

(1R,2R)-(-)-Pseudoephedrine may be used in the preparation of chiral relay ligands, which can catalyze the addition of diethylzinc to aldehydes leading to the corresponding secondary alcohol. The immobilization of pseudoephedrine on Merrifield resin forms a chiral linker, which may be used for the asymmetric alkylation of amides via solid-phase approach.

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H314,H317,H336
• 防範說明: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves