134910

(1R,2S)-(-)-麻黄碱

98%

• 别名: (-)-麻黄碱, (1R,2S)-(-)-α-(1-甲基氨基乙基)苄醇, (1R,2S)-(-)-2-甲氨基-1-苯丙醇, L-盐酸麻黄碱
• 线性分子式: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS号: 299-42-3
• 分子量: 165.23
• Beilstein: 2208730
• EC 号: 206-080-5
• MDL编号: MFCD00064257
• UNSPSC代码: 12352116
• PubChem化学物质编号: 24848190
• NACRES: NA.22

属性

• 质量水平: 200
• 方案: 98%
• 表单: solid
• 旋光性: [α]21/D −41°, c = 5 in 1 M HCl
• 沸点: 255 °C (lit.)
• mp: 37-39 °C (lit.)
• 密度: 1.124 g/mL at 25 °C (lit.)
• 官能团: amine; hydroxyl; phenyl
• 储存温度: 2-8°C
• SMILES字符串: CN[C@@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1
• InChI key: KWGRBVOPPLSCSI-WPRPVWTQSA-N

说明

一般描述

(1R,2S)-(-)-Ephedrine, a chiral β-amino alcohol, is commonly used as a chiral auxiliary in asymmetric synthesis. It undergoes reduction to form (+)-methamphetamine.

应用

通用手性合成子，用于催化以及制备光学纯亚砜和噁唑烷。

(1R,2S)-(-)-Ephedrine can be used in the preparation of optically active phosphine-phosphonite ligands and chirally-substituted cyclopentadienyl (Cp) ligands. It reacts with phosphorus trichloride to form (2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine. It can also act as a chiral resolving agent for (±)-mandelic acid.

安全信息

• 象形图: GHS05,GHS07
• 警示用语：: Danger
• 危险声明: H302,H314,H317
• 预防措施声明: P260 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危险分类: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
• 储存分类代码: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• 闪点(°F): 186.8 °F - closed cup
• 闪点(°C): 86 °C - closed cup
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves