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Merck

TLR7

toll-like receptor 7

别名:
TLR7-like
物种:
UniProtKB ID:
基因ID:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • dog(491743) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7

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Small Molecule - Agonist

货号
说明
物种
咪喹莫特, ≥98% (HPLC), solid,
物种
human
咪喹莫特, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
羟氯喹 硫酸酯, ≥98% (HPLC), powder,
物种
human
硫酸羟氯喹, United States Pharmacopeia (USP) Reference Standard,
物种
human
羟氯喹, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
硫酸羟氯喹, analytical standard,
物种
human
2-[4-[(7-氯-4-喹啉基)氨基]戊基]氨基乙醇, British Pharmacopoeia (BP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunocytochemistry

western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
物种反应性
human
应用

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tlr7,
物种
mouse
MISSION® esiRNA, targeting human TLR7,
物种
human