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P0928

Sigma-Aldrich

Resorufin pentyl ether

Synonyme(s) :

7-Pentyloxy-3-phenoxazone, 7-Pentyloxy-3H-phenoxazin-3-one, O7-Pentylresorufin, Pentoxyresorufin

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About This Item

Formule empirique (notation de Hill):
C17H17NO3
Numéro CAS:
87687-03-4
Poids moléculaire :
283.32
Numéro Beilstein :
8394939
Numéro MDL:
MFCD00037664
Code UNSPSC :
12161501
ID de substance PubChem :
24898138
Nomenclature NACRES :
NA.47

Pureté

≥98% (TLC)

Niveau de qualité

200

Forme

powder

Solubilité

acetonitrile: 0.95- 1.05 mg/mL, clear, orange

Température de stockage

2-8°C

Chaîne SMILES 

CCCCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3

Clé InChI

ZPSOKQFFOYYPKC-UHFFFAOYSA-N

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Description générale

Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.

Application

Resorufin pentyl ether has been used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.

Actions biochimiques/physiologiques

Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Advances in Microbial Ecology null
E S Tzanakakis et al.
Cell motility and the cytoskeleton, 48(3), 175-189 (2001-02-27)
Cultured rat hepatocytes self-assemble into three-dimensional structures or spheroids that exhibit ultrastructural characteristics of native hepatic tissue and enhanced liver-specific functions. The spheroid formation process involves cell translocation and changes in cell shape, indicative of the reorganization of the cytoskeletal
A Pietersma et al.
Free radical research, 28(2), 137-150 (1998-06-30)
The present study was undertaken to investigate the hypothesis that multiple oxygen radical generating systems contribute to the tumor necrosis factor (TNF) alpha-stimulated transcriptional activation of the vascular cell adhesion molecule (VCAM)-1 in endothelial cells. Experimental evidence has implicated the
Microbial Biofilms null
R B van Breemen et al.
Drug metabolism and disposition: the biological fate of chemicals, 26(2), 85-90 (1998-03-28)
An on-line mass spectrometric method has been developed to generate and identify drug metabolites formed by hepatic cytochromes P450. This method, pulsed ultrafiltration-mass spectrometry, may be used for rapid screening of drugs to determine their extent of metabolism by microsomal
Afficher tous les articles scientifiques apparentés

Articles

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

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