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B1532

Sigma-Aldrich

Resorufin benzyl ether

CYP450 substrate, ≥98% (TLC), powder

Synonyme(s) :

7-Benzyloxy-3H-phenoxazin-3-one, 7-Benzyloxyresorufin, O7-Benzylresorufin

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About This Item

Formule empirique (notation de Hill):
C19H13NO3
Numéro CAS:
87687-02-3
Poids moléculaire :
303.31
Numéro MDL:
MFCD00171613
Code UNSPSC :
12352204
ID de substance PubChem :
24891597
Nomenclature NACRES :
NA.32

product name

Resorufin benzyl ether, CYP450 substrate

Niveau de qualité

200

Pureté

≥98% (TLC)

Forme

powder

Solubilité

chloroform: 9.80-10.20 mg/mL, clear, orange

Température de stockage

2-8°C

Chaîne SMILES 

O=C1C=CC2=Nc3ccc(OCc4ccccc4)cc3OC2=C1

InChI

1S/C19H13NO3/c21-14-6-8-16-18(10-14)23-19-11-15(7-9-17(19)20-16)22-12-13-4-2-1-3-5-13/h1-11H,12H2

Clé InChI

XNZRYTITWLGTJS-UHFFFAOYSA-N

Substrats

Fluorimetric substrate for cytochrome P450-linked enzymes.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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The O-dealkylation of pentoxyresorufin, a substrate for P450 2B1, was decreased in lung microsomes from rats dosed with O,O,S-trimethylphosphorodithioate, O,O,O-trimethylphosphorothioate, bromophos, fenitrothion, p-xylene and 2,4-dichloro-(6-phenylphonoxy)ethylamine. This activity was decreased by antibodies to P450 2B1 but unaffected by antibodies to P450
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