901904

tBuXPhos

95%

• Synonyme(s) : 2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl, t-Bu XPhos, tert-Butyl XPhos
• Formule empirique (notation de Hill): C₂₉H₄₅P
• Numéro CAS: 564483-19-8
• Poids moléculaire : 424.64
• Numéro MDL: MFCD06411306
• Code UNSPSC : 12352002
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 95%
• Forme: powder or crystals
• Capacité de réaction: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• Pertinence de la réaction: reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• Pf: 148-151 °C (lit.); 150 °C
• Groupe fonctionnel: phosphine
• Chaîne SMILES: CC(P(C(C=CC=C1)=C1C(C(C(C)C)=CC(C(C)C)=C2)=C2C(C)C)C(C)(C)C)(C)C
• InChI: 1S/C29H45P/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12/h13-21H,1-12H3
• Clé InChI: SACNIGZYDTUHKB-UHFFFAOYSA-N

Description

Description générale

tBuXPhos [2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Application

tBuXPhos has been used in the preparation of [tBuXPhosAu(MeCN)]BAr₄F, a gold catalyst for the intermolecular [2+2] cycloaddition of terminal arylalkynes with substituted alkenes to form functionalized cyclobutenes with high regioselectivity.

Informations légales

Usage subject to Patents: EP 1097158; JP 5758844; CA 2336691

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable