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95212

Sigma-Aldrich

L-acide ascorbique

tested according to Ph. Eur.

Synonyme(s) :

Acide L-thréoascorbique, Facteur anti-scorbut, Vitamine C

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About This Item

Formule empirique (notation de Hill):
C6H8O6
Numéro CAS:
50-81-7
Poids moléculaire :
176.12
Numéro Beilstein :
84272
Numéro CE :
200-066-2
Numéro MDL:
MFCD00064328
Code UNSPSC :
12352205
ID de substance PubChem :
329770428
Nomenclature NACRES :
NA.21

Source biologique

synthetic

Agence

USP/NF
tested according to Ph. Eur.

Pureté

99.0-100.5%

Forme

solid

Couleur

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

Pf

190-194 °C (dec.)

Solubilité

water: soluble 176 g/L at 20 °C

Chaîne SMILES 

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

Clé InChI

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Informations sur le gène

human ... SLC23A2(9962)

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Catégories apparentées

Description générale

L-Ascorbic acid is the most biologically active form of ascorbic acid. It is hydrophilic and an unstable compound. L-Ascorbic acid contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid, also referred to as Vitamin C, is a water-soluble vitamin. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation. Vitamin C is a part of citrus fruits, such as broccoli, strawberries, turnip.

Application


  • Targeted screening of multiple anti-inflammatory components from Chrysanthemi indici Flos by ligand fishing with affinity UF-LC/MS: This study investigates the application of L-Ascorbic acid in enhancing the screening of anti-inflammatory compounds, utilizing its properties to stabilize reactive samples in cell cultures (Huang et al., 2024).

  • Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso: Demonstrates the use of L-Ascorbic acid in the evaluation of antioxidant properties of plant extracts, which is crucial in the pharmaceutical research of natural products (Kabore et al., 2024).

Actions biochimiques/physiologiques

L-Ascorbic acid functions according to its oxido-reduction property. It is a co-factor for hydroxylation. The biochemical actions of L-ascorbic acid is dependent on the activity of monoxygenase. It is involved in carnitine, collagen synthesis and production of neurotransmitters. Vitamin C exhibits anti-oxidant properties. Vitamin C plays a role in providing protection against photoaging and anti-aging effect. Deficiency of vitamin C leads to scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCL9955
BCCK6856
BCCJ1563
BCCJ1562
BCCG9487

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Consulter la Bibliothèque de documents

Vitamin C in health and disease: its role in the metabolism of cells and redox state in the brain
Figueroa M R and Rivas A S
Frontiers in Physiology, 6(4), 397-397 (2015)
Topical vitamin C and the skin: mechanisms of action and clinical applications
Al-Niaimi F and Chiang N Y Z
The Journal of Clinical and Aesthetic Dermatology, 10(7), 14-14 (2017)
Vitamin C in disease prevention and cure: an overview
Chambial S, et al.
Indian Journal of Clinical Biochemistry : IJCB, 28(4), 314-328 (2013)
Takashi Yoshida et al.
Nature chemical biology, 2(11), 596-607 (2006-09-26)
Transient receptor potential (TRP) proteins form plasma-membrane cation channels that act as sensors for diverse cellular stimuli. Here, we report a novel activation mechanism mediated by cysteine S-nitrosylation in TRP channels. Recombinant TRPC1, TRPC4, TRPC5, TRPV1, TRPV3 and TRPV4 of
Marc P Bradshaw et al.
Critical reviews in food science and nutrition, 51(6), 479-498 (2011-09-21)
Extensive reviews of research are available on the use of ascorbic acid, and its consequent degradation pathways, in physiological conditions or food matrices. However, very little information can be found for wine-related systems. This review highlights the relevant chemistry and
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