50137-U

LiChrospher^® RP-18 (5 µm) HPLC Columns

L × I.D. 25 cm × 4 mm, HPLC Column

• Sinónimos: TM=["LiChrospher"] C18 HPLC column
• Código UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Propiedades

• product name: Columna para HPLC LiChrospher^® RP-18, 5 μm particle size, L × I.D. 25 cm × 4 mm
• Materiales: stainless steel column
• Agency: suitable for USP L1
• Línea del producto: LiChrospher^®
• Características: endcapped: no
• fabricante / nombre comercial: LiChrospher^®
• envase: 1 ea of
• Extensión del etiquetado: 21% Carbon loading
• Parámetros: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• técnicas: HPLC: suitable
• L × D.I.: 25 cm × 4 mm
• superficie: 350 m²/g
• matriz: octadecyl; silica particle platform; fully porous particle
• grupo activo de la matriz: C18 (octadecyl) phase
• tamaño de partícula: 5 μm
• tamaño de poro: 100 Å
• pH operativo: 2-7.5
• aplicaciones: food and beverages
• técnica de separación: reversed phase

Descripción

Descripción general

LiChrospher^® RP-18 HPLC column (L × I.D. 25 cm × 4 mm) is found to be reliable and high versatile. Suitable for reversed-phase high performance liquid chromatography (RP-HPLC) of acidic, neutral and weakly basic compounds, according to L1 USP specifications.

Aplicación

• HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study developed and validated HPLC-UV and GC-MS methods for determining chlorambucil and valproic acid in plasma, aiming to explore their combined therapy for chronic lymphocytic leukemia. The LiChrospher^® RP-18 HPLC Column was instrumental in achieving the separation and quantification (Lipska et al., 2021).


• Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.: This research utilized the LiChrospher^® RP-18 HPLC Column for the rapid determination of metronidazole and its metabolite in murine blood plasma, highlighting its effectiveness in pharmacokinetic studies (Zemanová et al., 2022).


• Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This paper presents a chemometric approach to developing and validating an HPLC method for estimating ropinirole hydrochloride, utilizing the LiChrospher^® RP-18 column for precise and accurate results (Fatima et al., 2019).


• A New Solid-Phase Extraction Method for Determination of Pantoprazole in Human Plasma Using High-Performance Liquid Chromatography.: The study developed a novel solid-phase extraction method for determining pantoprazole in human plasma using HPLC with the LiChrospher^® RP-18 column, achieving high sensitivity and specificity (Zendelovska et al., 2019).


• Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.: This research employed the LiChrospher^® RP-18 column in an HPLC-MS/MS method to identify and assign related impurities in teicoplanin drug substances, demonstrating the column′s capability in impurity profiling (Tengattini et al., 2019).

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Información legal

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable