U1752

Uridine 5′-monophosphate

≥98%

• Sinónimos: U 5′-P, UMP, Uridylic acid
• Fórmula empírica (notación de Hill): C₉H₁₃N₂O₉P
• Número de CAS: 58-97-9
• Peso molecular: 324.18
• Número CE: 200-408-0
• Número MDL: MFCD00067346
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24900628
• NACRES: NA.51

Propiedades

• origen biológico: natural (organic)
• Ensayo: ≥98%
• Formulario: powder
• solubilidad: H₂O: soluble 50 mg/mL, clear, colorless
• temp. de almacenamiento: −20°C
• cadena SMILES: OC1C(O)C(OC1COP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)
• Clave InChI: DJJCXFVJDGTHFX-UHFFFAOYSA-N

Descripción

Descripción general

Uridine 5′-monophosphate acts as a precursor for all pyrimidine nucleotides.[1]

Aplicación

Uridine 5′-monophosphate has been used as a component in isotonic E3 medium for isotonic reconstitution experiments to study its effects on the basal cell response or epithelial cell migration to the wound in the isotonic medium.[2]

Acciones bioquímicas o fisiológicas

Uridine 5′-monophosphate (UMP) is a nucleotide monomer in RNA. It contains the nucleobase uracil along with the ribose sugar and a phosphate group. UMP dietary supplementation enhances neurotransmitter release and neurite outgrowth and also promotes membrane phosphatide production in adult rats.[3] Oral supplementation of DHA, co-administered with UMP, in adult gerbils shows an increase in dendritic spines and neuronal membrane synthesis. It suggests a strategy for the treatment of cognitive disorders resulting from synapse loss.[4]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)