SAB4700267

Monoclonal Anti-CD64 antibody produced in mouse

clone 10.1, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-FCGR1, Anti-FcγRI
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 10.1, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human, nonhuman primates
• concentración: 1 mg/mL
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NM_000566.3
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FCGR1(2209)

Descripción

Descripción general

The mouse monoclonal antibody 10.1 recognizes alpha subunit of CD64/FcgammaRI, a 72 kDa single chain type I glycoprotein, that is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes.

Inmunógeno

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Aplicación

Cluster of differentiation 64 (CD64) has been implicated in various immunological processes such as phagocytosis, the clearance of immune complexes and the secretion of immunological mediators. In addition, it also facilitates antibody-dependent cellular cytotoxicity, the modulation of B-cell differentiation and transcytosis of IgG across the epithelial layer. Neutrophil CD64 serves as a potent diagnostic marker for bacterial infection and neonatal sepsis.

Acciones bioquímicas o fisiológicas

The cluster of differentiation 64 (CD64), also known as Fc fragment of IgG receptor Ia (FCGR1A), gene is mapped to human chromosome lq21.2--q21.3. The gene codes for a 72 kDa glycoprotein that is constitutively expressed on human monocytes and macrophages.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable