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M2295

Sigma-Aldrich

Myelin Basic Protein from guinea pig brain

≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain

Sinónimos:

MBP

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About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.32

origen biológico

guinea pig brain

Análisis

≥80% (SDS-PAGE)

formulario

lyophilized powder

técnicas

cell based assay: suitable

Nº de acceso UniProt

aplicaciones

cell analysis

temp. de almacenamiento

−20°C

Información sobre el gen

guinea pig ... MBP(100731253)

Descripción general

Myelin Basic Protein (MBP) expressed in guinea pig brain contains 167 amino acids and has a molecular weight of 18,256Da.
Research area: Cell SignallingMyelin basic protein (MBP) is an important constituent of the myelin sheath of CNS (central nervous system). It is an auto-immunogen.

Aplicación

Myelin Basic Protein fromguinea pig brain has been used as a kinase substrate: to analyse in vitrokinase activity, in protein phosphorylation analysis, in ATG1 kinaseassay

Acciones bioquímicas o fisiológicas

Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis.
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.

Calidad

May contain traces of urea-glycine buffer salts.

Principio

Used as a kinase substrate.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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