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A7236

Anacardic acid

Histone Acetyl transferase (HAT) inhibitor, powder

Sinónimos:

2-Hydroxy-6-pentadecylbenzoic acid, 22:0-Anacardic acid, 6-Pentadecylsalicylic acid

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A ustedes/SKUDisponibilidadPrecio
5 mg

Disponible para enviar HOYdesdeLyon

151,00 €
25 mg
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593,00 €

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Fórmula empírica (notación de Hill):
C22H36O3
Número CAS:
Peso molecular:
348.52
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
Storage condition:
protect from light

151,00 €


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Nombre del producto

Anacardic acid,

form

powder

Quality Segment

storage condition

protect from light

color

white to beige

solubility

DMSO: ≥20 mg/mL

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O

InChI

1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)

InChI key

ADFWQBGTDJIESE-UHFFFAOYSA-N

Application

Anacardic acid has been used:
  • as a histone acetylase (HAT) inhibitor to study its effects on rat cortical neuronsPMID 27990351
  • as a positive control in acetylation assay in vitroPMID 28059601
  • as an acetylase inhibitor to study its effects on the ribonucleic acid export 1 (Rae-1) protein acetylation that was transfected in human embryonic kidney cellsPMID 33279621

Biochem/physiol Actions

Anacardic acid is a natural bioactive compound derived from the nutshell of Anacardium occidentale. It possesses anti-fungal, anti-bacterial, anti-termite, and molluscicidales activities. Anacardic acid acts as a therapeutic agent against obesity, cancer, inflammatory disorders, and oxidative damage. It functions as an inhibitor of various enzymes such as lipoxygenase (LOX-1), xanthine oxidase, nuclear factor κ B (NFκB) kinase, tyrosinase, and ureases.PMID 22103711
Anacardic acid is a HAT (Histone Acetyltransferase) inhibitor.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Este artículo
172050UC305SML1619
description

-

description

The Anacardic Acid, also referenced under CAS 16611-84-0, modulates the biological activity of Anacardic. This small molecule/inhibitor is primarily used for Cell Structure applications.

description

-

description

≥98% (HPLC)

form

powder

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 10 mg/mL, ethanol: 10 mg/mL, methanol: 10 mg/mL

solubility

-

solubility

DMSO: 20 mg/mL, clear

storage condition

protect from light

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

color

white to beige

color

white

color

white

color

white to light brown


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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