P4347
Propylene Glycol
meets USP testing specifications
Sinónimos:
1,2-Propanediol
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About This Item
Fórmula lineal:
CH3CH(OH)CH2OH
Número de CAS:
Peso molecular:
76.09
Beilstein:
1340498
Número CE:
Número MDL:
Código UNSPSC:
12161700
ID de la sustancia en PubChem:
NACRES:
NA.25
Productos recomendados
Agency
USP/NF
meets USP testing specifications
Nivel de calidad
densidad de vapor
2.62 (vs air)
presión de vapor
0.08 mmHg ( 20 °C)
temp. de autoignición
779 °F
lim. expl.
12.5 %
índice de refracción
n20/D 1.432 (lit.)
bp
187 °C (lit.)
mp
−60 °C (lit.)
densidad
1.036 g/mL at 25 °C (lit.)
aplicaciones
general analytical
pharmaceutical (small molecule)
sample preparation
cadena SMILES
CC(O)CO
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
Clave InChI
DNIAPMSPPWPWGF-UHFFFAOYSA-N
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Descripción general
Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations.
Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.
The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.
Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.
The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.
Aplicación
Propylene glycol has been used:
- for removing excess Oil Red O stain in zebrafish larvae
- in the preparation of alginate hydrogels
- for the dissolution of androstenone
- for the calibration of cone beam scanner in computed tomography
Características y beneficios
- Versatile and adaptable for a wide variety of laboratory and research applications
- Meets USP testing specifications
Otras notas
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Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
219.2 °F - closed cup
Punto de inflamabilidad (°C)
104 °C - closed cup
Equipo de protección personal
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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