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Merck

N0800000

Nikethamide

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

N,N-Diethylnicotinamide, Nicotinic acid diethylamide, ‘Nikethamide’

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About This Item

Fórmula empírica (notación de Hill):
C10H14N2O
Número de CAS:
Peso molecular:
178.23
Beilstein:
5743
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

nikethamide

fabricante / nombre comercial

EDQM

índice de refracción

n20/D 1.524 (lit.)

bp

296-300 °C (lit.)

mp

23 °C (lit.)

densidad

1.06 g/mL at 25 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CCN(CC)C(=O)c1cccnc1

InChI

1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

Clave InChI

NCYVXEGFNDZQCU-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Nikethamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbones

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 3 Oral - Eye Irrit. 2

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

235.4 °F - closed cup

Punto de inflamabilidad (°C)

113 °C - closed cup


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Certificados de análisis (COA)

Lot/Batch Number

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Determination of nikethamide and N-ethylnicotinamide in the blood and urine of greyhounds.
Lewis J H.
Journal of Chromatography A, 172, 295-302 (1979)
Lili Chen et al.
Journal of pharmaceutical and biomedical analysis, 43(5), 1757-1762 (2007-02-10)
Nikethamide and lidocaine are often requested to be quantified simultaneously in forensic toxicological analysis. A simple reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed for their simultaneous determination in human blood and cerebrospinal fluid. The method involves simple
Nathaly Reyes-Garcés et al.
Journal of chromatography. A, 1374, 40-49 (2014-12-03)
Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matrix interferences capable of inducing ionization suppression/enhancement

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