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G7651

Sigma-Aldrich

Glutaraldehyde solution

Grade I, 50% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

Sinónimos:

Glutaric dialdehyde solution, Pentane-1,5-dial

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About This Item

Fórmula lineal:
OHC(CH2)3CHO
Número de CAS:
111-30-8
Peso molecular:
100.12
Beilstein:
605390
Número MDL:
MFCD00007025
Código UNSPSC:
12352114
ID de la sustancia en PubChem:
24895318
NACRES:
NA.21

Nivel de calidad

300

tpo

Grade I

Formulario

liquid

concentración

50% in H2O

técnicas

electron microscopy: suitable (fixative)

color

colorless

mp

-21  °C ((-6 °F))

solubilidad

water: soluble

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

Clave InChI

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

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Descripción general

Glutaraldehyde is a saturated dialdehyde, which is widely known as a chemical sterilant. Glutaraldehyde solutions comprise both monomers and polymers with a difference in their fixation efficiency. 

Aplicación

Glutaraldehyde solution has been used:
  • along with 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer to fix the concentrated extracellular vesicles (EVs) on concanavalin A for scanning electron microscope (SEM)
  • as a component in a solution to fix the cells to observe its morphology
  • to fix the Escherichia coli cells in aqueous solution to preserve the surface morphology of bacterial cells

Acciones bioquímicas o fisiológicas

Glutaraldehyde is applicable in biomedical research to fix cells and can also be used to analyze healthy and pathologic red blood cells.

Características y beneficios

  • Highly efficient and safe to use with lensed instruments, rubber, or plastics 
  • Non-corrosive to metals
  • Minimum shelf life of 14 days

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Cláusula de descargo de responsabilidad

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Órganos de actuación

Respiratory system

Riesgos supl.

EUH071

Código de clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000370288
0000371186
0000370288
0000371186
0000267888

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Stéphane Jauréguiberry et al.
Blood, 124(2), 167-175 (2014-05-27)
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
Stephanie J Bissel et al.
Journal of neuropathology and experimental neurology, 74(8), 767-777 (2015-06-27)
Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is associated with seizures and destructive periventricular white matter lesions. Despite unremarkable cerebrospinal fluid (CSF), HPeV3 RNA can
Irene Costantini et al.
Scientific reports, 5, 9808-9808 (2015-05-08)
Extensive mapping of neuronal connections in the central nervous system requires high-throughput µm-scale imaging of large volumes. In recent years, different approaches have been developed to overcome the limitations due to tissue light scattering. These methods are generally developed to
Ming Fang et al.
BMC neuroscience, 16, 84-84 (2015-11-27)
Scutellarin, an anti-inflammatory agent, effectively suppressed microglia activation in rats with middle cerebral artery occlusion (MCAO). Robust microglia activation, acute in onset, was followed by astrogliosis. This study was aimed to determine if scutellarin would also affect the reactive astrocytes
Jamie Hinks et al.
Applied and environmental microbiology, 81(6), 1949-1958 (2015-01-13)
The modification of microbial membranes to achieve biotechnological strain improvement with exogenous small molecules, such as oligopolyphenylenevinylene-conjugated oligoelectrolyte (OPV-COE) membrane insertion molecules (MIMs), is an emerging biotechnological field. Little is known about the interactions of OPV-COEs with their target, the
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