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81210

Sigma-Aldrich

Poli(etilenglicol)

average Mw 1,500

Sinónimos:

PEG

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About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
25322-68-3
Número MDL:
MFCD00081839
Código UNSPSC:
12352104
ID de la sustancia en PubChem:
24887690
NACRES:
NA.23

product name

Poli(etilenglicol), average Mw 1,500

formulario

solid

Nivel de calidad

200

mol peso

average Mw 1,500

mp

45-50 °C

temperatura de transición

Tm 45-50 °C

Ω-final

hydroxyl

α-final

hydroxyl

cadena SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descripción general

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Aplicación

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Otras notas

Molecular weight range: 1,400-1,600

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCK3982
BCCH2553
BCCH2552
BCCD3122
BCCB0461

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Poli(etilenglicol) average mol wt 400

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P3265

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Poli(etilenglicol) average Mn 2,050, chips

Sigma-Aldrich

295906

Poli(etilenglicol)

DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
Relloso M et al.
Journal of Immunology, 168, 2634-2634 (2002)
Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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Artículos

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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