This product is not a sterile preparation. If the intended use, such as in cell culture, requires a sterile environment, then the stock solution would require filter sterilization. Typically, this is achieved by filtration through a 0.22 um membrane. Alternatively, product S9133 is a γ-irradiated, sterile powder. When reconstituted aseptically using sterile water, this product may be added directly to culture medium.
Please see the link below to review this product option:
https://www.sigmaaldrich.com/product/sigma/s9133
S5261
Sodium selenite
BioReagent, suitable for cell culture, ≥98%
Sinónimos:
Selenious acid, Sodium salt
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10 G
61,60 €
25 G
125,00 €
100 G
247,00 €
61,60 €
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10 G
61,60 €
25 G
125,00 €
100 G
247,00 €
About This Item
Fórmula lineal:
Na2SeO3
Número de CAS:
Peso molecular:
172.94
Número CE:
Número MDL:
Código UNSPSC:
12352205
ID de la sustancia en PubChem:
NACRES:
NA.75
61,60 €
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Productos recomendados
origen biológico
synthetic (inorganic)
Nivel de calidad
Línea del producto
BioReagent
Ensayo
≥98%
Formulario
powder
técnicas
cell culture | mammalian: suitable
mp
>350 °C (lit.)
solubilidad
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
cadena SMILES
[Na+].[Na+].[O-][Se]([O-])=O
InChI
1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
Clave InChI
BVTBRVFYZUCAKH-UHFFFAOYSA-L
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Aplicación
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
Producto relacionado
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Riesgos supl.
Código de clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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need filtration (0.2um) after preparation?
1 respuesta-
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How long does an aliquot of this product in water remain stable at -20 degrees Celsius?
1 respuesta-
As mentioned on the Product Datasheet, stock solutions of sodium selenite may be frozen. Working aliquots remain active for 30 days at 2-8 °C. The Datasheet can accessed in the DOCUMENTATION section under 'More Documents'. Please see the link below:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/245/224/s5261pis.pdf¿Le ha resultado útil?
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What solvent do I need to use? DMSO OK?
1 respuesta-
This item is soluble in water at 50mg/mL. The solubility in DMSO as not been tested.
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