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Merck

202398

Sigma-Aldrich

Poli(etilenglicol)

greener alternative

average Mn 400, hydroxyl

Sinónimos:

PEG

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5 G
23,60 €
250 G
26,70 €
500 G
30,30 €
20 KG
815,00 €

23,60 €


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5 G
23,60 €
250 G
26,70 €
500 G
30,30 €
20 KG
815,00 €

About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
Número MDL:
Código UNSPSC:
12352104
ID de la sustancia en PubChem:
NACRES:
NA.23

23,60 €


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Nombre del producto

Poli(etilenglicol), average Mn 400

Formulario

viscous liquid

Nivel de calidad

mol peso

Mn 380-420
average Mn 400

características de los productos alternativos más sostenibles

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

índice de refracción

n20/D 1.466

pH

4.5-7.5

viscosidad

7.3 cSt(210 °F)(lit.)

mp

4-8 °C (lit.)

densidad

1.128 g/mL

Ω-final

hydroxyl

α-final

hydroxyl

categoría alternativa más sostenible

cadena SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descripción general

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are non-toxic, FDA-approved, generally non-immunogenic, and frequently used in many biomedical applications including bioconjugation, drug delivery, surface functionalization, and tissue engineering. In drug delivery, PEGs can be used as linkers for antibody-drug conjugates (ADCs) or as a surface coating on nanoparticles to improve systemic drug delivery.

Aplicación

Poly(ethylene glycol) (PEG) has been used as a coating agent for the synthesis and in vitro safety assessment of magnetic bacterial cellulose (MBC) pellicles, performed on porcine aortic smooth muscle cells (PAOSMC). PEG provides a compatible surface for cell culture, since uncoated iron oxide NPs are considered cytotoxic to cells.[1] It has also been used as a plasticizer in investigating the effectiveness of polyvinylpyrrolidone microneedles for transdermal delivery of functional collagen using porcine skin, adult human skin analog and human foreskin. Microneedles obtained, were reportedly characterized by various analytical and bio-analytical techniques.[2]
Used in conjunction with carbon black to form a conductive composite.[3] Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.[4]

Información legal

Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves


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Certificados de análisis (COA)

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Visite la Librería de documentos

Transdermal delivery of functional collagen via polyvinylpyrrolidone microneedles
Sun W, et al.
Annals of Biomedical Engineering, 43(12), 2978-2990 (2015)
Changxin Wan et al.
Cancer research, 81(1), 158-173 (2020-11-08)
Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in HGSC are unknown. Here we performed immune functional and single-cell RNA sequencing transcriptional profiling on novel
Ruth Hernandez-Perez et al.
Physical review. E, 96(6-1), 062803-062803 (2018-01-20)
The evaporation of droplets can give rise to a wide range of interesting phenomena in which the dynamics of the evaporation are crucial. In this work, we find simple scaling laws for the evaporation dynamics of axisymmetric droplets pinned on
Akashi, M., Akagi, T.
Yuki Gosei Kaguku Kyokaishi, 65, 520-520 (2004)
Synthesis and in vitro safety assessment of magnetic bacterial cellulose with porcine aortic smooth muscle cells
Pastrana FH, et al.
Journal of Biomedical Materials Research Part A, 104(11), 2801-2809 (2016)

Contenido relacionado

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Preguntas

1–3 de 3 Preguntas  
  1. Hi, I wanted to know how did you prepare the PEG 400 into liquid form as it in my concern it might not be 100 % PEG would it be like 90% of PEG powdered form in aqueou solution or so on. I will be thankful if you provide answer of my this query.

    1 respuesta
    1. The specific manufacturing process for the product is proprietary. PEG400 is a pure liquid form of polyethylene glycol with no other components, and its viscous nature is a characteristic feature of the product.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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