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MAB4343

Sigma-Aldrich

Anti-SOX-2 Antibody

clone 6F1.2, Chemicon®, from mouse

Sinónimos:

Anti-ANOP3, Anti-MCOPS3

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

6F1.2, monoclonal

reactividad de especies

mouse, human

envase

antibody small pack of 25 μg

fabricante / nombre comercial

Chemicon®

técnicas

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

entrada

sample type: mouse embryonic stem cell(s)
sample type neural stem cell(s)
sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)

isotipo

IgG2b

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

ambient

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... SOX2(6657)
mouse ... Sox2(20674)

Descripción general

Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.

Inmunógeno

Recombinant GST Fusion protein.

Aplicación

Anti-SOX-2 Antibody detects level of SOX-2 & has been published & validated for use in IC, IH & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Calidad

Tested

Descripción de destino

~34 kDa

Forma física

Format: Purified
Purified Immunoglobulin by protein A affinity chromatography and presented as a liquid in 0.02 M phosphate buffer, pH 7.6, with 0.25 M NaCl. Contains 0.1% sodium azide.

Almacenamiento y estabilidad

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Masoumeh Fakhr Taha et al.
BioMed research international, 2014, 941486-941486 (2014-08-26)
The expression pattern of pluripotency markers in adipose tissue-derived stem cells (ADSCs) is a subject of controversy. Moreover, there is no data about the signaling molecules that regulate these markers in ADSCs. In the present study, we studied the roles
Valentina Poletti et al.
PloS one, 10(5), e0126590-e0126590 (2015-05-16)
Genome-wide mapping of transcriptional regulatory elements is an essential tool for understanding the molecular events orchestrating self-renewal, commitment and differentiation of stem cells. We combined high-throughput identification of transcription start sites with genome-wide profiling of histones modifications to map active
High-content imaging-based screening of microenvironment-induced changes to stem cells.
Vega, SL; Liu, E; Patel, PJ; Kulesa, AB; Carlson, AL; Ma, Y; Becker, ML; Moghe, PV
Journal of Biomolecular Screening null
Weixiang Guo et al.
Nature protocols, 7(11), 2005-2012 (2012-10-20)
In adult mammals, the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone of the dentate gyrus (DG) show ongoing neurogenesis, and multipotent neural stem or progenitor cells (NSCs) in these two regions exhibit different intrinsic properties. However
Ying Li et al.
Scientific reports, 6, 38665-38665 (2016-12-08)
Notch1 signaling plays a critical role in maintaining and determining neural stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific expression in NSPCs remains incomplete. Here, we show transcription factor Nkx6.1 interacts with a cis-element (CR2, an evolutionarily

Artículos

Skip weekend feedings. Defined serum-free and feeder-free expansion media for human pluripotent stem cells (ES and iPS cells). See publications and protocols.

The Simplicon™ RNA Reprogramming Technology is a next generation reprogramming system that uses a single synthetic, polycistronic self-replicating RNA strand engineered to mimic cellular RNA to generate human iPS cells.

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