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790404P

Avanti

18:1 DGS-NTA(Ni)

Avanti Research™ - A Croda Brand

Sinónimos:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt); DOGS NTA

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5 MG
166,00 €
10 MG
342,00 €
25 MG
483,00 €

166,00 €

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5 MG
166,00 €
10 MG
342,00 €
25 MG
483,00 €

About This Item

Fórmula empírica (notación de Hill):
C53H93N2O15Ni
Número de CAS:
231615-77-3
Peso molecular:
1057.00
Número MDL:
MFCD00056438
Código UNSPSC:
12352211
NACRES:
NA.25

166,00 €

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descripción

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is a conjugated phospholipid[1] that contains nickel.[2] NTA chelates with four of the six coordination sites present in nickel ion.[3]

Aplicación

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt) (18:1 DGS-NTA(Ni)) has been used:
  • in the preparation of liposomes with porphyrin-phospholipid (PoP) conjugate for protein and peptide binding studies[1]
  • in the preparation of nanosize multillamelar vesicles (NMVs) for antigen delivery studies[2]
  • as a component of small unilamellar vesicle (SUV) for planar lipid membrane (PM) preparation[4]

Acciones bioquímicas o fisiológicas

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is useful in structural biology especially to bind recombinant histidine tagged proteins.[1] Though useful, being nanoparticulate it has stability problems in biological samples. So NTA-lipid conjugate is majorly used as liposomes or as a coating to nanoparticle.[1] DGS-NTA (Ni) based nanosize multillamelar vesicles (NMVs) are potent vaccine delivery system.[2]

Envase

5 mL Clear Glass Sealed Ampule (790404P-10mg)
5 mL Clear Glass Sealed Ampule (790404P-25mg)
5 mL Clear Glass Sealed Ampule (790404P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

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Elizabeth M Wilson-Kubalek et al.
Methods in enzymology, 481, 45-62 (2010-10-05)
Helical protein arrays offer unique advantages for structure determination by cryo-electron microscopy (cryo-EM). A single image of such an array contains a complete range of equally spaced molecular views of the underlying protein subunits, which allows a low-resolution, isotropic three-dimensional
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Transmembrane receptors in the signaling pathways of bacterial chemotaxis systems influence cell motility by forming noncovalent complexes with the cytoplasmic signaling proteins to regulate their activity. The requirements for receptor-mediated activation of CheA, the principal kinase of the Escherichia coli
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Cell, 125(6), 1137-1149 (2006-06-17)
The mechanism by which the epidermal growth factor receptor (EGFR) is activated upon dimerization has eluded definition. We find that the EGFR kinase domain can be activated by increasing its local concentration or by mutating a leucine (L834R) in the
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