Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 201-208 (1999-10-16)
An in vitro permeation study of ethyl nicotinate (EN) was carried out using excised hairless rat skin, and simultaneous skin transport and metabolism of the drug were kinetically followed. Fairly good steady-state fluxes of EN and its metabolite nicotinic acid
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(1), 11-16 (2008-11-18)
Mononuclear copper(II) saccharinate (sac) complex containing ethylnicotinate (enc), [Cu(enc)(2)(sac)(2)(H(2)O)].1.4H(2)O has been synthesized and characterized by spectroscopic (IR, UV-vis, EPR), X-ray diffraction technique and electrochemical methods. It crystallizes in the tetragonal crystal systems with space group I4(1)cd and Z=8. The copper(II)
Journal of pharmaceutical sciences, 72(2), 142-145 (1983-02-01)
The kinetic barrier against the transport of methyl and ethyl nicotinates across the water-isopropyl myristate interface has been studied as a function of temperature using a rotating diffusion cell. The temperature dependence of the interfacial transfer kinetics has enabled calculation
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 58(3), 645-651 (2004-09-29)
The skin transport and metabolism characteristics of ethyl nicotinate (EN) in rabbit, rat, guinea-pig, pig, shed snake skin and human were compared. In vitro skin transport using excised skin and hydrolysis experiments using skin homogenate were carried out. Flux of
European journal of medicinal chemistry, 43(9), 1818-1827 (2008-02-05)
2-(alicyclic-amino)-4,6-diaryl-3-pyridinecarboxylates 5a-d were prepared via aromatic nucleophilic substitution reaction of secondary amines (piperidine or morpholine) with 2-bromo-3-pyridinecarboxylate derivatives 3a,b. The latters were obtained through bromination of 3-aryl-4-benzoyl-2-cyanobutyrates 2a and 2b, which were obtained from the base promoted addition of ethyl
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