The Journal of otolaryngology, 34(5), 297-303 (2005-09-27)
To develop an evidence-based algorithm for determining the etiology of bilateral sensorineural hearing loss (SNHL) in a child. The frequency of different etiologies was previously determined. A systematic review of the literature for articles published between 1940 and January 2003
The Journal of biological chemistry, 285(4), 2580-2590 (2009-11-27)
Collagen triple helices are stabilized by 4-hydroxyproline residues. No function is known for the much less common 3-hydroxyproline (3Hyp), although genetic defects inhibiting its formation cause recessive osteogenesis imperfecta. To help understand the pathogenesis, we used mass spectrometry to identify
Identification of 3-hydroxyproline residues in several proteins of Fasciola hepatica.
Collagens are among proteins that undergo several post-translational modifications, such as prolyl hydroxylation, that occur during elongation of the nascent chains in the endoplasmic reticulum. The major structural collagens, types I, II and III, have large, uninterrupted triple helices, comprising
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