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Merck

HTR5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

Sinónimos:
5-HT5A
Especie:
Human HTR5A (3361), Mouse Htr5a (15563), Rat Htr5a (25689), cow HTR5A (541200), Horse HTR5A (100063709), domestic cat HTR5A (101084611), Zebrafish htr5a (100038775), dog HTR5A (482814), sheep HTR5A (101116905), naked mole-rat Htr5a (101723065) ...Más
ID UniProtKB:
P47898, Q2M2D2
ID del gen:
  • Human(3361) Summary: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
  • Mouse(15563) 5-hydroxytryptamine (serotonin) receptor 5A
  • Rat(25689) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • cow(541200) 5-hydroxytryptamine (serotonin) receptor 5A
  • Horse(100063709) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic cat(101084611) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • Zebrafish(100038775) 5-hydroxytryptamine (serotonin) receptor 5A
  • dog(482814) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • sheep(101116905) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • naked mole-rat(101723065) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic guinea pig(100379278) 5-hydroxytryptamine (serotonin) receptor 5A
  • chicken(428409) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Especie
human, rat
F112
(+)-Fenfluramine hydrochloride, ,
Especie
human
Q1004
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Especie
human, rat
A2729
Amisulpride, ≥98% (HPLC),
Especie
human
BP1143
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Especie
human
A0590000
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Y0001534
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4501483
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
western blot
SAB2900156
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
SAB2900036
Anti-HTR5A (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
SAB2900037
Anti-HTR5A (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, dog, guinea pig, horse, human, monkey, mouse, rat
Aplicación
ELISA
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human
F132
Fluoxetina hydrochloride, solid,
Especie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Especie
human
R0875
Reserpine, ,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
HTS141M
ChemiSCREEN Membrane Preparation Recombinant Human 5-HT5A Serotonin Receptor, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU104651
MISSION® esiRNA, targeting human HTR5A,
Especie
human