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F1678

R-(−)-Fluoxetine hydrochloride

Name: R-(−)-Fluoxetine hydrochloride
Brand: SIGMA
Price: 83.13 EUR

>98% (HPLC), solid

Sinónimos:

(R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride

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A ustedes/SKU	Disponibilidad	Precio
5 mg	Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad	97,80 € 83,13 €
25 mg	Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad	346,00 €

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₁₇H₁₈NOF₃ · HCl

Número CAS:

114247-09-5

Peso molecular:

345.79

NACRES:

NA.77

PubChem Substance ID:

24278433

UNSPSC Code:

12352200

MDL number:

MFCD04040065

Assay:

>98% (HPLC)

Form:

solid

Storage condition:

desiccated

83,13 €

Precio de catálogo97,80 €Ahorre 15 %

Promoción solo por Internet

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Propiedades

Quality Segment

100

assay

>98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H₂O: soluble >10 mg/mL

originator

Eli Lilly

SMILES string

Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1

InChI key

GIYXAJPCNFJEHY-PKLMIRHRSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Descripción

Application

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

to study its effects on the embryoid body (EB) morphogenesis
in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
to study its effects as an endocrine disruption inducer in Pimephales promelas

Biochem/physiol Actions

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Este artículo	F132	343290	D054
Sigma-Aldrich F1678 R-(−)-Fluoxetine hydrochloride	Sigma-Aldrich F132 Fluoxetina hydrochloride	Sigma-Aldrich 343290 Fluoxetine, Hydrochloride	Sigma-Aldrich D054 R(+)-SCH-23390 hydrochloride
description >98% (HPLC), solid	description solid	description A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI).	description ≥98% (HPLC), solid
form solid	form solid	form solid	form solid
assay >98% (HPLC)	assay -	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
solubility H₂O: soluble >10 mg/mL	solubility H₂O: 4 mg/mL, DMSO: >5 mg/mL	solubility water: 5 mg/mL, methanol: 100 mg/mL	solubility H₂O: >5 mg/mL
storage condition desiccated	storage condition -	storage condition OK to freeze, protect from light, desiccated (hygroscopic)	storage condition desiccated, protect from light
originator Eli Lilly	originator Eli Lilly	originator -	originator -

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pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H315,H318

pcodes

P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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