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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Sinónimos:
EPND, GluN2A, NMDAR2A, NR2A
Especie:
ID UniProtKB:
ID del gen:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Especie
rat
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Especie
human
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dextromethorphan hydrobromide, meets USP testing specifications,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
4-Aminopiperidine, ,
Especie
rat
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
(±)-Ketamine hydrochloride, solid,
Especie
human
S-(+)-Ketamine hydrochloride, ,
Especie
human
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Glicina, ReagentPlus®, ≥99% (HPLC),
Especie
rat
Glicina, suitable for electrophoresis, ≥99%,
Especie
rat
Glicina, BioUltra, for molecular biology, ≥99.0% (NT),
Especie
rat
Glicina, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Especie
rat
Glicina, ,
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-NR2A, clon A12W, monoclonal de conejo, culture supernatant, clone A12W, Upstate®,
Reactividad de especies
mouse, rat
Aplicación
western blot
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Reactividad de especies
fish, human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-NR2A Antibody, Upstate®, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho NMDAR2A (Ser1459), ,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Especie
human
Agmatine sulfate salt, ≥97%, powder,
Especie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Especie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Indole-2-carboxylic acid, 98%,
Especie
rat, human
1,3-Diphenylguanidine, 97%,
Especie
rat, mouse, human
Quisqualic acid, powder,
Especie
rat
Nω-Nitro-L-arginine, ≥98% (TLC),
Especie
rat, mouse, human
Pentamidine isethionate salt, powder,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
1,3-Diaminopropane, ≥99%,
Especie
rat
N,N′-Dimethyl-1,3-propanediamine, 97%,
Especie
rat
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Especie
rat
1,3-Diamino-2-propanol, 95%,
Especie
rat
2,2-Dimethyl-1,3-propanediamine, 99%,
Especie
rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GRIN2A,
Especie
human
MISSION® esiRNA, targeting mouse Grin2a,
Especie
mouse