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Principaux documents

MAK068

Sigma-Aldrich

MPO Colorimetric Activity Assay Kit

sufficient for 100 colorimetric tests

Synonyme(s) :

Myeloperoxidase Colorimetric Activity Assay Kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric tests

Méthode de détection

colorimetric

Maladie(s) pertinente(s)

cancer; cardiovascular diseases; hematological disorder

Température de stockage

−20°C

Informations sur le gène

human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)

Description générale

Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.

Application

MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.

Caractéristiques et avantages

Compatible with high-throughput handling systems.

Adéquation

Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells

Principe

In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H315,H319,H334

Classification des risques

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Point d'éclair (°F)

188.6 °F

Point d'éclair (°C)

87 °C

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
8F23K07440
7L08K07440
7G02K07440
7B17K07440
6L24K07440

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Ruisong Pei et al.
Molecular nutrition & food research, 63(5), e1800985-e1800985 (2018-12-07)
Increased fruit consumption is associated with reduced risk of colitis. It has been investigated whether the anti-colitic effects of the polyphenol-rich aronia berry (Aronia mitschurinii 'Viking') are mediated through Th17 and Treg. Colitis is induced in recombinase activating gene-1 deficient
Plasma nitration of high-density and low-density lipoproteins in chronic kidney disease patients receiving kidney transplants.
Bakillah A, et al.
Mediators of Inflammation, 2015 (2015)
Ivan Luzardo-Ocampo et al.
Food research international (Ottawa, Ont.), 132, 109097-109097 (2020-04-26)
Ulcerative colitis (UC) is a condition that has been rising in the number of cases around the world. Food products made from natural ingredients such as corn and common bean might serve as alternatives for the treatment of UC. This
Mary Caitlin P Sok et al.
Acta biomaterialia, 53, 109-122 (2017-02-19)
Many goals in tissue engineering rely on modulating cellular localization and polarization of cell signaling, including the inhibition of inflammatory infiltrate, facilitation of inflammatory cell egress, and clearance of apoptotic cells. Omega-3 polyunsaturated fatty acid-derived resolvins are gaining increasing recognition
Caffeic acid phenethyl amide ameliorates ischemia/reperfusion injury and cardiac dysfunction in streptozotocin-induced diabetic rats.
Ho Y J, et al.
Cardiovascular Diabetology, 13(1), 98-98 (2014)
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