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RAB0374

Sigma-Aldrich

Mouse MPO ELISA Kit

for plasma and cell culture supernatant

Synonyme(s) :

MPO, Myeloperoxidase

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

mouse

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 600 pg/mL
standard curve range: 0.61-150 ng/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

mouse ... Mpo(17523)

Catégories apparentées

Description générale

The Mouse MPO (Myeloperoxidase) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MPO in plasma and cell culture supernatants.

Immunogène

Recombinant Mouse Myeloperoxidase

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Actions biochimiques/physiologiques

Myeloperoxidase (MPO) has a crucial role to play in the destruction of various microorganisms and foreign cells, such as bacteria, fungi, viruses, red cells, and malignant and nonmalignant nucleated cells. MPO catalyzes the production of number of reactive oxidant species (ROS) that influence tissue damage during inflammation. MPO and its downstream inflammatory pathways function as a potent therapeutic target for prophylaxis of atherosclerotic cardiovascular disease. MPO catalyzes the synthesis of polychlorinated dibenzo(p)dioxins and furans (PCDD/F) from precursors such as chlorophenols in the presence of hydrogen peroxide (H2O2).

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Description
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  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)FDS
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  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS
  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Sebastian Mayer-Rollnik et al.
European journal of anaesthesiology, 37(3), 180-186 (2019-12-05)
Postoperative autologous retransfusion of drainage blood might reduce the transfusion of red blood cell concentrates after major orthopaedic surgery. Our primary objective was to evaluate the effectiveness of a blood collection and retransfusion system. Secondary objectives included safety issues and
Myeloperoxidase and cardiovascular disease.
Nicholls SJ and Hazen SL
Arteriosclerosis, Thrombosis, and Vascular Biology, 25, 1102-1111 (2005)
Nour Eissa et al.
Scientific reports, 7, 42427-42427 (2017-02-12)
2,4-Dinitrobenzene sulfonic acid (DNBS)-induced colitis is an experimental model that mimics Crohn's disease. Appropriateness of reference genes is crucial for RT-qPCR. This is the first study to determine the stability of reference gene expression (RGE) in mice treated with DNBS.
Clinical manifestation of myeloperoxidase deficiency.
Lanza F, et al.
Journal of Molecular Medicine, 76, 676-681 (1998)
Michael A Pazos et al.
PLoS pathogens, 13(8), e1006548-e1006548 (2017-08-05)
Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A3 (HXA3), initiating neutrophil transepithelial migration. Migrated neutrophils amplify this recruitment by
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