440153

L-α-lysophosphatidylinositol sodium salt

>99% (HPLC), powder, GPR55 agonist, Calbiochem^®

• Synonyme(s) : L-α-lysophosphatidylinositol Sodium Salt, Soy, L-α-lysophosphatidylinositol LPI, Lyso PI, Soy Lyso PI
• Formule empirique (notation de Hill): C₂₅H₄₈NaO₁₂P
• Numéro CAS: 796963-91-2
• Poids moléculaire : 594.61
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: L-α-lysophosphatidylinositol Sodium Salt, Soy, A potent agonist and assumed endogenous ligand of GPR55.
• Niveau de qualité: 100
• Pureté: >99% (HPLC)
• Forme: powder
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic); protect from light
• Couleur: white
• Solubilité: DMSO: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

Description

Description générale

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable