Mucins are soluble in water, forming hazy viscous solutions.
M1778
Mucine from porcine stomach
Type III, bound sialic acid 0.5-1.5 %, partially purified powder
Synonyme(s) :
MUC
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About This Item
Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Source biologique
Porcine stomach
Niveau de qualité
Type
Type III
Forme
partially purified powder
Composition
bound sialic acid, 0.5-1.5%
Technique(s)
microbiological culture: suitable
Solubilité
NaOH: soluble 20 mg/mL
Température de stockage
2-8°C
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Catégories apparentées
Description générale
Application
Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.[3]
Actions biochimiques/physiologiques
Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.[4]
Notes préparatoires
Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Certificats d'analyse (COA)
Lot/Batch Number
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The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
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Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
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The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known
Articles
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
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Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...
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What does the "Type" designation in Mucin from porcine stomach mean?
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The type designation does not have any particular biological significance. It is used to emphasize differences in the listings of this product.
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What are the differences between Mucin from porcine stomach Products M2378 and M1778?
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Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.
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Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?
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This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.
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What is the molecular weight of Product M1778, Mucin from porcine stomach?
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This product is partially purified from crude mucin, M2378. Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.
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How can I solubilize Product M1778, Mucin from porcine stomach?
1 answer-
Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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