900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Synonyme(s) : Carboxyl sulfonyl fluoride alkyne, Probe building block
• Formule empirique (notation de Hill): C₁₂H₁₃FO₄SSi
• Numéro CAS: 2088829-06-3
• Poids moléculaire : 300.38
• Numéro MDL: MFCD30737995
• Code UNSPSC : 12352106
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: ≥95%
• Forme: solid
• Pertinence de la réaction: reagent type: cross-linking reagent
• Disponibilité: available only in USA
• Température de stockage: −20°C
• Chaîne SMILES: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

Description

Application

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H242,H315,H319
• Conseils de prudence: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• Classification des risques: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• Code de la classe de stockage: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable