U9382

Ubiquitin-Carrier Protein H10 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution

• Synonym(e): UbcH10
• MDL-Nummer: MFCD03458906
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Qualitätsniveau: 200
• Rekombinant: expressed in E. coli (histidine-tagged)
• Assay: ≥95% (SDS-PAGE)
• Form: buffered aqueous glycerol solution
• Mol-Gew.: ~20 kDa
• Methode(n): ligand binding assay: suitable
• UniProt-Hinterlegungsnummer: O00762
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... UBE2C(11065)

Beschreibung

Allgemeine Beschreibung

Manufactured for Sigma by Boston Biochem., Inc.

Anwendung

Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.

Biochem./physiol. Wirkung

In conjunction with anaphase-promoting complex, catalyzes both cyclin A and cyclin B destruction.

In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.

Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.[1]

Physikalische Form

Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.

Sicherheitshinweise

• WGK: WGK 1