SML3208

CPYPP

≥98% (HPLC)

• Synonym(e): 4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
• Empirische Formel (Hill-System): C₁₈H₁₃ClN₂O₂
• CAS-Nummer: 310460-39-0
• Molekulargewicht: 324.76
• MDL-Nummer: MFCD00980987
• UNSPSC-Code: 51111800
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: orange to dark red
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
• InChI: 1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
• InChIKey: VVZJFICTTKPNCK-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.

cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids