R137

Ro 31-0432

solid

• Synonym(e): 3-(8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)-4-(1-methylindol-3-yl)maleimide hydrochloride, 3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione monohydrochloride, Bisindoylmaleimide XI
• Empirische Formel (Hill-System): C₂₈H₂₈N₄O₂ · HCl
• CAS-Nummer: 145333-02-4
• Molekulargewicht: 489.01
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824001
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥98% (TLC)
• Form: solid
• Lagerbedingungen: protect from light
• Farbe: orange
• Löslichkeit: DMSO: 5 mg/mL; H₂O: insoluble
• Lagertemp.: −20°C
• SMILES String: Cl.CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26
• InChI: 1S/C28H28N4O2.ClH/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21;/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34);1H
• InChIKey: HSPRASOZRZDELU-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Protein kinase C (PKC) inhibitor; membrane-derived PKC inhibitor.

Leistungsmerkmale und Vorteile

This compound is featured on the GRKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Vorsicht

Photosensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)