O2751

Natrium-Oxamat

≥98%

• Synonym(e): Aminooxoessigsäure Natriumsalz, Oxalsäure-monoamid Natriumsalz, Oxamidsäure Natriumsalz
• Lineare Formel: NH₂COCOONa
• CAS-Nummer: 565-73-1
• Molekulargewicht: 111.03
• Beilstein: 6538153
• EG-Nummer: 209-290-5
• MDL-Nummer: MFCD00044553
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24278607
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥98%
• Form: powder
• mp (Schmelzpunkt): 300 °C
• Löslichkeit: water: 50 mg/mL, clear, colorless
• SMILES String: [Na+].NC(=O)C([O-])=O
• InChI: 1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
• InChIKey: RQVZIJIQDCGIKI-UHFFFAOYSA-M

Beschreibung

Anwendung

Sodium oxamate has been used:

• as one of the variable in flow injection analysis[1]
• in in vitro angiogenesis assay[2]
• to confirm the stimulatory role of stearic acid on lactate dehydrogenase mediated lactate production[3]

Biochem./physiol. Wirkung

Sodium oxamate influences the fatty acid metabolism.[4] It might be useful for the treatment of diabetes.[5]

Structural analog of pyruvate, inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway[6]. Binding studies with lactate dehydrogenase[7]; Mechanism of inhibition of mitochondrial pyruvate metabolism[8]

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)