It is shipped at ambient temperature, but it is to be stored at 2-8 °C for long term storage. Do not FREEZE as it is in a buffered aqueous solution.
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N7271
α(2→3)-Neuraminidase aus Streptococcus pneumoniae
buffered aqueous solution
Synonym(e):
Acyl-Neuraminyl-Hydrolase, Acylneuraminyl-Hydrolase, Receptor-destroying enzyme, Sialidase
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.2 UNIT
1.060,00 €
1.060,00 €
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.2 UNIT
1.060,00 €
About This Item
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.32
1.060,00 €
Auf LagerDetails
Empfohlene Produkte
Biologische Quelle
Streptococcus pneumoniae
Qualitätsniveau
Form
buffered aqueous solution
Konzentration
≥5 units/mL
Fremdaktivität
β-Galactosidase, α-mannosidase, β-hexosaminidase, α-fucosidase, and proteases, none detected
Versandbedingung
wet ice
Lagertemp.
2-8°C
Angaben zum Gen
Streptococcus pneumoniae R6 ... nanB(933504)
Biochem./physiol. Wirkung
Releases α(2→3)-linked N-acetylneuraminic acid from complex oligosaccharides.
Verpackung
Provided with 5× reaction buffer (250 mM sodium phosphate, pH 6.0).
Einheitendefinition
One unit will hydrolyze 1μmole of 4-methylumbelliferyl α-D-N-acetylneuraminide per min at pH 5.0 at 37 °C.
Physikalische Form
Solution in 50 mM sodium phosphate, pH 7.5
Angaben zur Herstellung
Expressed in glycosidase-free hosts.
Signalwort
Danger
H-Sätze
P-Sätze
Gefahreneinstufungen
Resp. Sens. 1
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Johan Nordholm et al.
The Journal of biological chemistry, 288(15), 10652-10660 (2013-03-01)
Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1-N9) and the
Audu J Natala et al.
Journal of medical entomology, 50(1), 85-93 (2013-02-23)
Amblyomma variegatum F. are obligate hematophagous ectoparasites of livestock that serve as the vectors of Ehrlichia ruminantium (formerly known as Cowdria ruminantium), the causative agent of heartwater disease. In the light of the fact that they are blood-feeding, their salivary
Dominic Meusch et al.
Nature, 508(7494), 61-65 (2014-02-28)
Tripartite Tc toxin complexes of bacterial pathogens perforate the host membrane and translocate toxic enzymes into the host cell, including in humans. The underlying mechanism is complex but poorly understood. Here we report the first, to our knowledge, high-resolution structures
Jin-Hyo Kim et al.
Science (New York, N.Y.), 340(6128), 71-75 (2013-02-23)
Influenza antiviral agents play important roles in modulating disease severity and in controlling pandemics while vaccines are prepared, but the development of resistance to agents like the commonly used neuraminidase inhibitor oseltamivir may limit their future utility. We report here
Charng-Sheng Tsai et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(7), 2466-2471 (2013-01-30)
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) containing an alkyne group was shown to be a mechanism-based target-specific irreversible inhibitor of sialidases. The ester-protected analog DFSA (PDFSA) is a membrane-permeable precursor of DFSA designed to be used in living cells, and it was
Artikel
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
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What is the long term storage and shipping condition of ?(2—›3) Neuraminidase, Product No. N7271?
1 Antwort-
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What is the molecular weight of ?(2—›3) Neuraminidase, Product No. N7271?
1 Antwort-
The molecular weight of this ?(2—›3 Neuraminidase enzyme is approximately 75 kDa.
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What are the reaction conditions of the enzyme ?(2—›3) Neuraminidase, Product No. N7271?
1 Antwort-
One nanomole of substrate or less can be cleaved in a 20 μL reaction volume. In the standard reaction use: 4 μL of 5X enzyme reaction "buffer B" (=250 mM sodium phosphate buffer, pH 6.0), a combined volume of 14 μL containing purified oligosaccharide and water and 2 μL of NANase I (N7271). Incubate 1 hour at 37 °C. To cleave more than one nanomole of substrate, increase reaction volume and enzyme proportionally.
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For ?(2—›3) Neuraminidase, Product No. N7271, what is the optimum pH range for the neuraminidase enzyme activity?
1 Antwort-
The optimum pH range for ?(2—›3 neuraminidase is 6.0. Please see the data sheet.
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What is the Department of Transportation shipping information for this product?
1 Antwort-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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